Vildagliptin
Brief Introduction:
Vildagliptin is a DPP-4 enzyme inhibitor. DPP-4 enzyme inhibitors mainly enhance the effect of incretin by inhibiting DPP-4. DPP-4 enzyme inhibitors can increase the level of endogenous active GLP-1 by 2-3 times, thereby enhancing the sensitivity of β-cells and α-cells to glucose, that is to say, it can increase glucose-stimulated insulin secretion and enhance the inhibitory effect of glucose on glucagon secretion, thereby improving hyperglycemia.
Specifications of our Vildagliptin:
| Test Items | Specifications | |
| Character | White to yellowish white or grayish white powder | |
| Identification | It exhibits most strongest absorption at the wave numbers of about 3293cm-1, 2915cm-1, 2238cm-1, 1659cm-1, 1407cm-1, 1355cm-1 and 1151cm-1 | |
| Purity | Heavy Metals | Not more than 10 ppm |
| Related Substances 1 | L-Prolinamide: Not more than 0.10% | |
| AHA: Not more than 0.10% | ||
| Related Substances 2 | RRt about 0.6 impurity: Not more than 0.10% | |
| Related Substances 3 | Maximum impurity: Not more than 0.10% | |
| Total impurities: Not more than 0.50% | ||
| Enantiomer | RRt about 0.78 impurity: Not more than 0.10% | |
| Water | Not more than 0.5% | |
| Residue on Ignition | Not more than 0.1% | |
| Assay | 98.5% ~ 101.0% | |
| Foreign Matter Test | Fatal foreign matter: 0 | |
| Critical foreign matter: Not more than 2 | ||
| Minor foreign matter: Not more than 5 | ||
| Residual Solvents 1 | 2-Butanone: Not more than 5000 ppm | |
| Residual Solvents 2 | 2-Propanol: Not more than 5000 ppm | |
| Dichloromethane: Not more than 600 ppm | ||
| Triethylamine: Not more than 5000 ppm | ||
Packaging:
1kg/Aluminum Foil Bag, 20kg/Drum or according to the specific requirements from customers.
Storage Conditions:
Preserved in unopened original containers in a cool dry place before using; kept away from direct sunlight, heat and moisture.
Shelf Life:
24 months if stored under above mentioned conditions.
