(S)-(-)-2-Methyl-2-propanesulfinamide
Brief Introduction:
(S)-(-)-2-Methyl-2-propanesulfinamide, also known as (S)-tert-butylsulfinamide or Tert-butylsulfenamide, has a CAS number of 343338-28-3, an EINECS number of 640-158-3, and a chemical formula of C4H11NOS.
(S)-(-)-2-Methyl-2-propanesulfinamide is a new type of pharmaceutical intermediate developed in recent years and is also a key chiral source for the synthesis of chiral amine drugs and their intermediates.
Solubility:
Soluble in many organic solvents, such as ethanol, ether and chlorinated hydrocarbons.
Preparation Method:
(S)-(-)-2-Methyl-2-propanesulfinamide is generally prepared by reacting tert-butylsulfonyl chloride and ammonia in N,N-dimethylformamide.
Specifications of our (S)-(-)-2-Methyl-2-propanesulfinamide:
Test Items | Specifications |
Appearance | White to off-white solid |
Purity (LC-220nm) | Not less than 99% |
E.E. | Not less than 99% |
Water Content (KF) | Not more than 0.5% |
HNMR | Conforms |
Solubility (ACN) | Not less than 10 mg/mL(Clear solution) |
Applications:
♔ (S)-(-)-2-Methyl-2-propanesulfinamide is a chiral ligand used in pharmaceutical compositions.
♔ (S)-(-)-2-Methyl-2-propanesulfinamide condenses with aldehydes and ketones to form P, n-sulfoximine ligands, and can asymmetric hydrogenate olefins under iridium catalysis.
Packaging:
1kg/Aluminum Foil Bag, 5kg/Carton, 10kg/Carton, 25kg/Fibre Drum or according to the specific requirements from customers.
Storage Conditions:
Store in a sealed unopened container at a temperature ≤ 30°C and a humidity ≤ 75% RH; protect from heat, light and oxygen.
Shelf Life:
12 months if stored under above mentioned conditions.