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(S)-(-)-2-Methyl-2-propanesulfinamide

Short Description:

Product Name: (S)-(-)-2-Methyl-2-propanesulfinamide

Synonyms: S-(-)-T-Butylsulfinimide; (S)-tert-butylsulfinamide; (S)-(-)-T-Butylsulfinamide; (S)-(-)-T-Butyl Sulfinamide; (S)-(-)-Tert-Butylsulfinamide; (S)-(-)-Tert-Butyl Sulphinamide; (S)-(-)-T-Butylmethylsulfinamide; (S)-2-Methylpropane-2-Sulfinamide; S-(-)-2-Methyl-2-Propanesulfinamide; (S)-(-)-2-Methyl-2-Propanesulfinamide; (S)-(-)-2-Methyl-2-Propanesulphinamide; 2-Methyl-2-Propane-Sulfinamide(S-Isomer); (S)-(-)-2-Methyl-Propane-2-Sulfinic Acid Amide

CAS No.: 343338-28-3

EINECS No.: 640-158-3

Molecular Formula: C4H11NOS

Molecular Weight: 121.2


Product Detail

Product Tags

Brief Introduction:

(S)-(-)-2-Methyl-2-propanesulfinamide, also known as (S)-tert-butylsulfinamide or Tert-butylsulfenamide, has a CAS number of 343338-28-3, an EINECS number of 640-158-3, and a chemical formula of C4H11NOS.

 

(S)-(-)-2-Methyl-2-propanesulfinamide is a new type of pharmaceutical intermediate developed in recent years and is also a key chiral source for the synthesis of chiral amine drugs and their intermediates.

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Solubility:

Soluble in many organic solvents, such as ethanol, ether and chlorinated hydrocarbons.

Preparation Method:

(S)-(-)-2-Methyl-2-propanesulfinamide is generally prepared by reacting tert-butylsulfonyl chloride and ammonia in N,N-dimethylformamide.

Specifications of our (S)-(-)-2-Methyl-2-propanesulfinamide:

Test Items Specifications
Appearance White to off-white solid
Purity (LC-220nm) Not less than 99%
E.E. Not less than 99%
Water Content (KF) Not more than 0.5%
HNMR Conforms
Solubility (ACN) Not less than 10 mg/mL(Clear solution)

Applications:

♔ (S)-(-)-2-Methyl-2-propanesulfinamide is a chiral ligand used in pharmaceutical compositions.

 

♔ (S)-(-)-2-Methyl-2-propanesulfinamide condenses with aldehydes and ketones to form P, n-sulfoximine ligands, and can asymmetric hydrogenate olefins under iridium catalysis.

Packaging:

1kg/Aluminum Foil Bag, 5kg/Carton, 10kg/Carton, 25kg/Fibre Drum or according to the specific requirements from customers.

Storage Conditions:

Store in a sealed unopened container at a temperature ≤ 30°C and a humidity ≤ 75% RH; protect from heat, light and oxygen.

Shelf Life:

12 months if stored under above mentioned conditions.


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