Nonapeptide-1
Brief Introduction:
Nonapeptide-1 is a biomimetic nonapeptide that can antagonize α-MSH(α-melanocyte stimulating hormone) and thereby inhibit melanin formation. As a bionic peptide, this peptide can antagonize α-MSH and has a very good effect on controlling undesirable skin color and age spots.
Clinical studies have shown that it has a good whitening effect on Asians, is non-cytotoxic, and does not affect the function of melanocytes, which is an ideal skin whitening agent.
Sequence:
Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2
Specifications of our Nonapeptide-1:
| Test Items | Specifications |
| Appearance | White or off-white powder |
| Molecular Ion Mass | 1206.5 |
| Purity (HPLC) | Not less than 99.0% |
| Acetic Acid Content (HPLC) | Not more than 15.0% |
| TFA Content (HPLC) | Not more than 0.5% |
| Water Content (Karl Fischer) | Not more than 8.0% |
| pH Value (1% Aqueous Solution) | 5.5 ~ 7.5 |
| Peptide Content | Not less than 80.0% |
| Water Solubility | Not less than 100mg per ml |
Some Shortcomings of Traditional Whitening and Freckle Removal Raw Materials:
| Hydroquinone | It is cytotoxic and can easily cause permanent white spots. |
| Arbutin | It is photosensitive and not suitable for use during the day. |
| Kojic Acid | Easy to oxidize and irritating to skin. |
Characteristics that New Whitening Raw Materials Should Have:
♔ Can inhibit tyrosinase activity;
♔ Not toxic or mutagenic;
♔ Has proven clinical efficacy;
♔ Good stability in formulation;
♔ Protects the stability of the formula.
Whitening Mechanism & Controlled Trial:
Application Examples of the Whitening Agent Nonapeptide-1:
① La Prairie Skin Caviar Luxe Eye Cream;
② La Prairie White Caviar Illuminating Serum;
③ La Prairie White Caviar Illuminating Hand Cream SPF 15;
④ DRSATIN Caviar Hydrodynamic Moisturizing Miracle Essence;
⑤ DR. HU Multi-Peptide Gold Eye Mask.
Recommended Dosage:
1% ~ 8%
Packaging:
1g/bottle, 3g/bottle, 5g/bottle, 10g/bottle, 30g/bottle, 50g/bottle, 100g/bottle or according to the specific requirements from customers.
Storage Conditions:
Nonapeptide-1 should be stored in unopened original containers in a cool dry place before using; kept away from direct sunlight, heat and moisture; preserved at 2℃ to 8℃ for short-term storage, -20℃±5℃ for long-term storage.
Shelf Life:
24 months if stored under above mentioned conditions.
