L-Serine
Brief Introduction:
L-serine is an important amino acid, with CAS number: 56-45-1 and molecular formula: C3H7NO3. It is an important intermediate metabolite in organisms, a precursor of various amino acids, nucleotides, choline and phospholipids, and is involved in the synthesis of protein production, lipids, nucleic acids and neurotransmitters.
L-serine has a positive effect on brain health and cognitive function, may help control inflammatory reactions in the brain, and repair mental function in disease states. It also plays an important role in strengthening immune function and regulating regular sleep.
Chemical Structural Formula:
Physical & Chemical Properties:
| Characteristics | White crystal or crystalline powder, odorless, sweet |
| Relative Density | 1.6 |
| Boiling Point | 197.09℃(Rough Estimate) |
| Melting Point | 222℃(dec.) (lit.) |
| Flashing Point | 150℃ |
| Specific Rotation | 15.2°(c=10, 2N HCl) |
| Refractive Index | 1.4368(Estimate) |
| Acidity Coefficient | 2.19(At 25℃) |
| Water Solubility | 250 g/L(20℃) |
Specifications of our L-Serine EP Grade (Suitable for Medical Use):
| Test Items | Specifications |
| Characteristics | White or nearly white crystalline powder or colourless crystals, slightly sweet taste, easily soluble in water, insoluble in ethanol |
| Identification | It complies with the spectrum obtained with Serine |
| Specific Optical Rotation[α]D20 | +14.0° ~ +16.0° (on dried basis) |
| Loss on Drying | Not more than 0.5% |
| Residue on Ignition | Not more than 0.1% |
| Chloride | Not more than 200 ppm |
| Sulfate | Not more than 300 ppm |
| Heavy Metals | Not more than 0.001% |
| Iron | Not more than 10 ppm |
| Related Substances (TLC) | Any other impurity: ≤0.2% |
| Total impurities: ≤0.5% | |
| Chiral Assay | / |
| Assay | 98.5% ~ 101.0% |
Specifications of our L-Serine USP Grade (Suitable for the Food Industry):
| Test Items | Specifications |
| Characteristics | White crystals with sweet taste; soluble in water, hardly soluble in anhydrous ethanol and ether |
| Identification | It complies with the spectrum obtained with Serine |
| Specific Optical Rotation[α]D20 | +14.0° ~ +15.6° (on dried basis) |
| Loss on Drying | Not more than 0.2% |
| Residue on Ignition | Not more than 0.1% |
| Chloride | Not more than 0.05% |
| Sulfate | Not more than 0.03% |
| Iron | Not more than 0.003% |
| Related Substances (TLC) | Any other impurity: ≤0.5% |
| Total impurities: ≤2.0% | |
| Chiral Assay | / |
| Assay | 98.5% ~ 101.5% |
Specifications of our L-Serine AJI92 Grade (Suitable for the Cosmetics Industry):
| Test Items | Specifications |
| Description | White crystalline or crystalline powder, slightly sweet taste. The product is soluble in water and formic acid, almost insoluble in ethanol and ether. Dissolve in dilute |
| Identification | The IR absorption spectrum of this product should be consistent with the standard product spectrum or the reference spectrum (spectrum set 917) |
| Assay | 99.0% ~ 101.0% (on dried basis) |
| Chiral Assay | / |
| Specific Rotation[α]D20 | +14.4° ~ +15.5°(on dried basis) |
| pH Value | 5.2 ~ 6.2 |
| State of Solution | Not less than 98.0% |
| Chloride (Cl) | Not more than 0.020% |
| Ammonium (NH4+) | Not more than 0.02% |
| Sulfate (SO4) | Not more than 0.020% |
| Arsenic (As) | Not more than 1 ppm |
| Iron (Fe) | Not more than 10 ppm |
| Other amino acids (TLC) | Not more than 0.2% |
| Loss on Drying | Not more than 0.20% |
| Residue on Ignition | Not more than 0.10% |
| Heavy Metals | Not more than 10 ppm |
L-Serine is Widely Used in Medicine, Food, Cosmetics and Other Industries:
1) As biochemical reagents and food additives;
2) Nutritional supplements, the main role of skin stratum corneum to maintain moisture, key additives in advanced cosmetics;
3) It can be used for biochemical and nutritional research, and can also be used as a raw material for the synthesis of cycloserine;
4) Serine can promote the metabolism of fat and fatty acid and help maintain the immune system;
5) Synthesize precursors of purine, thymine and choline;
6) It has the function of stabilizing the pH value of eye drops, and is non-irritating after eye drops; it is one of the important natural moisturizing factors (NMF).
Packaging:
0.5kg/Aluminum foil bag, 1kg/Aluminum foil bag, 25kg/Fibre drum or according to the specific requirements from customers.
Storage Conditions:
Preserved in unopened original containers in a cool dry place before using; kept away from sunlight, heat and moisture.
Shelf Life:
24 months if stored under above mentioned conditions.
