L-Alpha glycerylphosphorylcholine
Brief Introduction:
L-Alpha glycerylphosphorylcholine(GPC) is also known as choline alfoscerate, choline phosphoglyceride, and glycerol lecithin. It is a product of phosphatidylcholine, which is the complete hydrolysis of two fatty acyl groups on lecithin molecules. It is a water-soluble phospholipid precursor and neurotransmitter naturally present in the human body, and it is also a unique cell protection agent. It supports the fluidity and integrity of cell membranes.
Years of experimental research and clinical application have shown that GPC can not only improve people's memory and cognitive ability, but also has a significant effect on the decline of brain circulation and Alzheimer's disease, so it is called the anti-aging nutrient of the brain. In addition, it can also resist muscle atrophy, protect blood vessels, etc.
Specifications of our L-Alpha glycerylphosphorylcholine(alpha GPC) 50%:
Test Items | Specifications | Test Methods |
Appearance | White powder, hygroscopic | Visual |
Identification | Conforms to the Standard | TLC |
Heavy Metals | Less than 10ppm | Colorimetry |
Moisture | Less than 3.0% | K. F |
Assay | Not less than 50.0% | Potentiometric Titration |
Total Plate Count | Not more than 1000CFU/g | CP |
Yeasts & Moulds | Not more than 100CFU/g | CP |
Coliforms | Negative | CP |
Salmonella | Negative | CP |
Specifications of our L-Alpha glycerylphosphorylcholine(alpha GPC) 99%:
Test Items | Specifications | Test Methods |
Appearance | White powder, neutral odour, highly hygroscopic | Visual |
Identification | TLC: Standard solution and test solution same pot, RF | TLC |
Specific Optical Rotation | -2.4° ~ -2.8° | / |
Heavy Metals(as Pb) | Not more than 10ppm | Colorimetry |
Sulfate(SO4) | Not more than 0.02% | Colorimetry |
Chloride(Cl) | Not more than 0.02% | Colorimetry |
pH Value | 4.5 ~ 7.0 | / |
Related Substances | Spot not bigger than Standard solution spot | TLC |
Residual Solvents | Less than 0.5% | HS-GC |
Water Content | Less than 2.0% | K. F |
Assay(On Dried Basis) | 98.0% ~ 102.0% | Potentiometric Titration |
Effects & Applications:
L-Alpha glycerylphosphorylcholine(alpha GPC) was confirmed as GRAS (Generally Recognized Safe Substance) by FDA in the United States in 2012, and is currently widely used in dietary supplements, food supplements, Nutritious functional foods, etc.
Based on available evidence, dietary GPC supplementation benefits:
1. Cultivation and maintenance of concentration, attention and memory;
2. Speed and overall clarity of thought processing;
3. Emotions, including positive attitudes and social skills;
4. Restoration of brain function after circulatory deprivation;
5. Restoring declining mental function;
6. Skeletal muscle integrity, including growth and regeneration;
7. Kidney and liver function, including renewal and detoxification;
8. Fertility, including sperm performance and fertilization ability, etc.
When L-A-glycerophosphorylcholine is used as a drug, the main indications are: suitable for cerebral ischemic attack (stroke or transient ischemic attack) within 10 days, mild to moderate Alzheimer's dementia, and Patients with multi-infarct dementia.
At the same time, it is a good medicine for protecting the liver and a prescription medicine for treating senile dementia. Indications vary from country to country, for example, South Korea: Alzheimer’s disease, memory loss, depression; Russia: cerebral ischemic stroke treatment, Alzheimer’s disease and memory loss; Vietnam: post-stroke rehabilitation, craniocerebral Trauma, trauma recovery, Alzheimer's disease, confusion, memory loss in the elderly.
♔ Main dosage forms: injection, capsule, oral solution
Packaging:
1kg/Aluminum foil bag, 25kg/Drum or according to the specific requirements from customers.
Storage Conditions:
Preserved in unopened original containers in a cool dry place before using; kept away from sunlight, heat and moisture.
Shelf Life:
24 months if stored under above conditions.