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L-Alpha glycerylphosphorylcholine

Short Description:

Product Name: L-Alpha glycerylphosphorylcholine

Abbreviation: alpha GPC

CAS No.: 28319-77-9

EINECS No.: 248-962-2

Molecular Formula: C8H20NO6P

Molecular Weight: 257.22


Product Detail

Product Tags

Brief Introduction:

L-Alpha glycerylphosphorylcholine(GPC) is also known as choline alfoscerate, choline phosphoglyceride, and glycerol lecithin. It is a product of phosphatidylcholine, which is the complete hydrolysis of two fatty acyl groups on lecithin molecules. It is a water-soluble phospholipid precursor and neurotransmitter naturally present in the human body, and it is also a unique cell protection agent. It supports the fluidity and integrity of cell membranes.

 

Years of experimental research and clinical application have shown that GPC can not only improve people's memory and cognitive ability, but also has a significant effect on the decline of brain circulation and Alzheimer's disease, so it is called the anti-aging nutrient of the brain. In addition, it can also resist muscle atrophy, protect blood vessels, etc.

甘磷酸胆碱化学结构式

Specifications of our L-Alpha glycerylphosphorylcholine(alpha GPC) 50%:

Test Items Specifications Test Methods
Appearance White powder, hygroscopic Visual
Identification Conforms to the Standard TLC
Heavy Metals Less than 10ppm Colorimetry
Moisture Less than 3.0% K. F
Assay Not less than 50.0% Potentiometric Titration
Total Plate Count Not more than 1000CFU/g CP
Yeasts & Moulds Not more than 100CFU/g CP
Coliforms Negative CP
Salmonella Negative CP

Specifications of our L-Alpha glycerylphosphorylcholine(alpha GPC) 99%:

Test Items Specifications Test Methods
Appearance White powder, neutral odour, highly hygroscopic Visual
Identification TLC: Standard solution and test solution same pot, RF TLC
Specific Optical Rotation -2.4° ~ -2.8° /
Heavy Metals(as Pb) Not more than 10ppm Colorimetry
Sulfate(SO4) Not more than 0.02% Colorimetry
Chloride(Cl) Not more than 0.02% Colorimetry
pH Value 4.5 ~ 7.0 /
Related Substances Spot not bigger than Standard solution spot TLC
Residual Solvents Less than 0.5% HS-GC
Water Content Less than 2.0% K. F
Assay(On Dried Basis) 98.0% ~ 102.0% Potentiometric Titration

Effects & Applications:

L-Alpha glycerylphosphorylcholine(alpha GPC) was confirmed as GRAS (Generally Recognized Safe Substance) by FDA in the United States in 2012, and is currently widely used in dietary supplements, food supplements, Nutritious functional foods, etc.

 

Based on available evidence, dietary GPC supplementation benefits:
1. Cultivation and maintenance of concentration, attention and memory;
2. Speed and overall clarity of thought processing;
3. Emotions, including positive attitudes and social skills;
4. Restoration of brain function after circulatory deprivation;
5. Restoring declining mental function;
6. Skeletal muscle integrity, including growth and regeneration;
7. Kidney and liver function, including renewal and detoxification;
8. Fertility, including sperm performance and fertilization ability, etc.

 

 

When L-A-glycerophosphorylcholine is used as a drug, the main indications are: suitable for cerebral ischemic attack (stroke or transient ischemic attack) within 10 days, mild to moderate Alzheimer's dementia, and Patients with multi-infarct dementia.

At the same time, it is a good medicine for protecting the liver and a prescription medicine for treating senile dementia. Indications vary from country to country, for example, South Korea: Alzheimer’s disease, memory loss, depression; Russia: cerebral ischemic stroke treatment, Alzheimer’s disease and memory loss; Vietnam: post-stroke rehabilitation, craniocerebral Trauma, trauma recovery, Alzheimer's disease, confusion, memory loss in the elderly.

 

Main dosage forms: injection, capsule, oral solution

Packaging:

1kg/Aluminum foil bag, 25kg/Drum or according to the specific requirements from customers.

Storage Conditions:

Preserved in unopened original containers in a cool dry place before using; kept away from sunlight, heat and moisture.

Shelf Life:

24 months if stored under above conditions.


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