Beta-Nicotinamide adenine dinucleotide disodium salt
Brief Introduction
Nicotinamide adenine dinucleotide (reduced coenzyme I) is a coenzyme that transfers protons (more precisely hydrogen ions) that occur in many metabolic reactions in cells. NADH or more precisely NADH + H+ is its reduced form. It can be reduced, carrying up to two protons (written as NADH + H+).
Physical & Chemical Properties
| Density | 1.955 at 20℃ |
| Melting Point | 140℃ ~ 142℃ |
| Water Solubility | Soluble |
| Vapor Pressure | 0.73Pa at 20℃-50℃ |
| Solubility | H2O: 50mg/mL |
| pH Value | 7.5 (100mg/mL in water, ±0.5) |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Sensitivity | Sensitive to light and easy to absorb moisture |
| Form | Powder |
| Surface Tension | 69.22mN/m at 1.022g/L and 20℃ |
Specifications of β-NADH
| Test Items | Specifications | |
| Appearance | White to yellowish powder | |
| Purity(HPLC) | ≥95% | |
| Assay of β-NADH(enzym.)(Calculated on sodium-free and anhydrous basis) | ≥90% | |
| Assay of β-NADH, Na2(enzym.)(Calculated on anhydrous basis) | ≥90% | |
| Sodium Content(IC) | 6.5%±1% | |
| Water Content(KF) | ≤8% | |
| pH Value(100mg/mL aqueous solution) | 7.0 ~ 10.0 | |
|
Heavy Metal Content(AAS) |
Lead(Pb) | ≤0.5 ppm |
| Arsenic(As) | ≤0.5 ppm | |
| Mercury(Hg) | ≤0.1 ppm | |
| Cadmium(Cd) | ≤0.5 ppm | |
| Total Plate Count(GB 4789.2) | ≤750CFU/g | |
| Coliforms(GB 4789.3) | ＜3MPN/g | |
| Moulds & Yeasts(GB 4789.15) | ≤50CFU/g | |
| Staphylococcus aureus | Negative | |
| Salmonella | Negative | |
Applications
Beta-nicotinamide adenine dinucleoside disodium is a biologically active form of niacin. Used as a coenzyme for hydrogenase and dehydrogenase. NAD normally acts as a hydrogen acceptor, forming NADH, which then acts as a hydrogen donor in the respiratory chain. It mainly exists in living cells in the reduced form (NADPH) and participates in synthetic reactions. Two forms occur, alpha-NAD and beta-NAD, characterized by the configuration of the ribosyl nicotinamide bond. Only the β-anomer is biologically active.
Packaging
Small quantities packed in Aluminum foil bags or food grade PE bags; Bulk packed in Cardboard Boxes or Drums.
Transport Conditions
Kept sealed, dry and protected from light for transportation under room temperature.
Storage Conditions
Kept dry and away from light, long-term storage at -25℃ to -15℃.
Shelf Life
24 months if stored under above conditions.
