Ademetionine Disulfate Tosylate
Brief Introduction:
S-Adenosyl-L-methionine Disulfate Tosylate, referred to as: SAM-T, is a natural molecule that exists in all cells of the human body. Concentrations are higher in the liver, adrenal gland and pineal gland, and evenly distributed in the brain.
S-Adenosyl-L-methionine Disulfate Tosylate has multiple protective effects on liver cells through mechanisms such as anti-oxidative free radicals and promotion of liver cell regeneration.
In recent years, studies have also found that S-Adenosyl-L-methionine Disulfate Tosylate can increase the fluidity of neuronal membranes in the brain of patients, promote the production of excitatory neurotransmitters, has an important dual role in improving the mood of liver disease patients and treating depression.
The concentration of SAM-T in the cerebrospinal fluid of patients can be increased by intravenous or oral medication. Adjuvant therapy for patients with mild to moderate depression is safer and more effective, bringing a broader space for the treatment of human "physiological-psychological" diseases.
Specifications of our S-Adenosyl-L-methionine Disulfate Tosylate(SAM-T):
| Test Items | Specifications | |
| Appearance | White to off-white powder | |
| Identification | Infrared | Conforms to the Reference Spectrum |
| HPLC | The retention time of the major peak corresponds to the reference sample | |
| Water Content(K. F) | Not more than 3.0% | |
| Sulphated Ash | Not more than 0.5% | |
| pH Value(5% Aqueous Solution) | 1.0 ~ 2.0 | |
| S,S-Isomer(HPLC) | Not less than 75.0% | |
| SAM-e ION(HPLC) | 49.5% ~ 54.7% | |
| P-Toluenesulfonic Acid | 21.0% ~ 24.0% | |
| Content of Sulfate(SO4) (HPLC) | 23.5% ~ 26.5% | |
| S-Adenosyl-L-methionine Disulfate Tosylate | 95.0% ~ 103.0% | |
| Related Substances(HPLC) | S-Adenosyl-L-Homocysteine | Not more than 1.0% |
| Adenine | Not more than 1.0% | |
| Methylthioadenosine | Not more than 1.5% | |
| Adenosine | Not more than 1.0% | |
| Single Unknown Impurities | Not more than 1.0% | |
| Total Impurities | Not more than 3.5% | |
| Heavy Metals | Not more than 10ppm | |
| Lead(Pb) | Not more than 3ppm | |
| Cadmium(Cd) | Not more than 1ppm | |
| Arsenic(As) | Not more than 1ppm | |
| Mercury(Hg) | Not more than 0.1ppm | |
| Microbiology | Total Plate Count | Not more than 1000CFU/g |
| Yeasts & Moulds | Not more than 100CFU/g | |
| Escherichia coli/10g | Negative | |
| Salmonella/10g | Negative | |
| Staphylococcus aureus/10g | Negative | |
Product Use and Impact on The Human Body:
1. Good Liver Nutrition：
S-Adenosyl-L-methionine Disulfate Tosylate has a protective effect on liver function in patients with liver cancer after TACE treatment, and the short-term effect of protecting acute liver injury is satisfactory.
2. Regulate Emotions, Antidepressant：
S-Adenosyl-L-methionine Disulfate Tosylate is a natural substance widely present in the body, and it participates in many important biological processes as a methyl donor. It has been found to have metabolic abnormalities in several psychiatric disorders, such as schizophrenia and affective disorders.
Medicinal grade S-Adenosyl-L-methionine Disulfate Tosylate is a potent antidepressant. It has the characteristics of definite curative effect, quick onset, small adverse reactions, and patients' willingness to accept it. Especially suitable for patients with chronic liver disease or poor physical condition and elderly patients.
3. Improve Joint Pain:
S-Adenosyl-L-methionine Disulfate Tosylate has anti-inflammation, relieves pain, promotes cartilage tissue formation and injury healing, maintains bone and joint health, and has a significant effect on various arthritis and joint injuries.
4. Improve Sleep
5. Adjuvant treatment of Parkinson's disease, pancreatitis, Alzheimer's disease, etc.
Packaging:
100g/Aluminum foil bag, 1kg/Aluminum foil bag, 25kg/drum or according to the specific requirements from customers.
Storage Conditions:
Preserved in unopened original containers in a cool dry place before using; kept away from sunlight, heat and moisture.
Shelf Life:
24 months if stored under above conditions.
