head_banner

Products

Acetazolamide

Short Description:

Product Name: Acetazolamide

Alias: 2-acetamido-5-sulfamoyl-1,3,4-thiadiazole; 5-acetamido-1,3,4-thiadiazole-2-sulfonamide; 2-ACETAMINO-1,3,4-THIADIAZOLE-5-SULFONAMIDE; N-(5-SULFAMOYL-1,3,4-THIADIAZOL-2-YL)ACETAMIDE; N-(5-SULFAMOYL-1,3,4-THIADIAZOL-2-YL)ETHANAMIDE; N-(5-[AMINOSULFONYL]-1,3,4-THIADIAZOL-2-YL)ACETAMIDE; N-[5-(AMINOSULFONYL)-1,3,4-THIADIOZOL-2-YL]-ACETAMIDE

CAS No.: 59-66-5

EINECS No.: 200-440-5

Molecular Formula: C4H6N4O3S2

Molecular Weight: 222.25


Product Detail

Product Tags

Brief Introduction:

Acetazolamide, whose chemical name is N-(5-SULFAMOYL-1,3,4-THIADIAZOL-2-YL)ACETAMIDE, also called 2-acetamido-5-sulfamoyl-1,3,4-thiadiazole or 5-acetamido-1,3,4-thiadiazole-2-sulfonamide, it is an organic compound with the chemical formula C4H6N4O3S2.

乙酰唑胺

Specifications:

Test Items Specifications
Description Characteristic White acicular crystalline or crystalline powder; odourless
Solubility Slightly soluble in boiling water, extremely slightly soluble in water or ethanol, almost insoluble in chloroform or ether, and soluble in ammonia
Identification Physical and chemical identification 1 Produces a white sediment
Physical and chemical identification 2 Produces a ethyl acetate aroma
Infrared Identification The infrared absorption spectrum of this product should match with that of the working standard (infrared absorption spectrum 9)
pH Value 4.0 ~ 6.0
The clarity of an alkaline solution The solution should be clarified
Chloride Not more than 0.014%
Sulphate Not more than 0.04%
Related Substances Total impurities shall be: Not more than 1.0%
The single impurity: Not more than 0.5%
Silver reduction Consumption of ammonium thiocyanate titrates (0.1mol/L) shall not be less than 4.8 ml
Loss on Drying Not more than 0.5%
Residue on Ignition Not more than 0.1%
Heavy Metals Not more than 20 ppm
Residual Solvents Glacial acetic acid: Not more than 0.5%
Acetonitrile: Not more than 0.041%
Assay 98.0% ~ 102.0% (C4H6N4O3S2)
Microbial Limits Total aerobic bacteria: Not more than 1000CFU/g
Total molds and yeasts: Not more than 100CFU/g

Applications:

Acetazolamide is a diuretic and carbonic anhydrase inhibitor. After taking it, it inhibits carbonic anhydrase in renal tubular epithelial cells, reducing the formation of H2CO3 and subsequently decreasing the production of H+. Therefore, the exchange of H+ and Na+ is greatly slowed down. As a result, the excretion of HCO3-, Na+, and K+ increases, then the urine output increases. It can also inhibit the aqueous humor secretion process and reduce intraocular pressure.

 

Acetazolamide can also be used to treat glaucoma, mild cardiac edema, etc.

Packaging:

1kg/bag, 20kg/drum or according to the specific requirements from customers.

Storage Conditions:

Preserved in unopened original containers in a cool dry place before using; kept away from direct sunlight, heat and moisture.

Shelf Life:

36 months if stored under above mentioned conditions.


  • Previous:
  • Next: