4-Butylresorcinol

Short Description:

Product Name: 4-Butylresorcinol

Alias: 4-Butyl-resorcinol; 4-butylresorcin; butylresorcinol; 4-N-BUTYLRESORCINOL; 4-Butylbenzene-1,3-diol; 4-phenylbutane-1,3-diol; 1,3-Benzenediol,4-butyl-; 2,4-Dihydroxy-n-bytyl benzen; 2,4-DIHYDROXY-N-BUTYL BENZEN; 2,4-DIHYDROXY-N-BUTYL BENZENE

CAS No.: 18979-61-8

Chemical Formula: C10H14O2

Molecular Weight: 166.22

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Brief Introduction:

4-Butylresorcinol, also called 4-butylresorcin, which is a chemical substance with a chemical formula of C10H14O2 and a molecular weight of 166.22. It is often used as a whitening additive in skin care products.

Specifications of our 4-Butylresorcinol:

Test Items		Specifications
Appearance		White to off-white powder
Odour		Characteristic
Assay		Not less than 99.0%
Loss on Drying		Not more than 1.0%
Melting Point		About 50.0℃
Residue on Ignition		Not more than 0.5%
Solubility		Soluble in methanol and methylene chloride, slightly soluble in water
Identification by IR		Meets the requirements
Related Substances	Resorcinol	Not more than 0.2%
	2,4-Dihydroxybutyrophenone	Not more than 0.5%
	Any other impurity	Not more than 1.0%
	Total impurities	Not more than 1.0%
Residual Solvents	Hexane	Not more than 100ppm
	Methanol	Not more than 500ppm
	Ethyl Acetate	Not more than 5000ppm

Effects:

4-Butylresorcinol is a high-efficiency skin whitening and brightening agent, which has the following effects:

1. Strong inhibitor of tyrosinase and peroxidase;
2. Effective skin whitening agent and toner for normal skin;
3. An effective whitening agent for pigmented skin;
4. Effective against chloasma (skin with hyperpigmentation exposed to sunlight);
5. It has a strong protective effect on DNA damage induced by H2O2;
6. Proved to have anti-glycation effect.

In the three processes of melanin source synthesis, 4-butylresorcinol not only has an important inhibitory effect on tyrosinase activity, but also has a synergistic effect on its whitening activity in the process:

♔ Before the synthesis of melanin, it interferes with the synthesis and glycosylation of tyrosinase to prevent the enzyme from being absorbed by melanosomes.

♔ During melanin synthesis, it inhibits the activity of enzymes, acts as a competitive inhibitor of tyrosinase and TRP1 enzymes, and reduces the formation of by-products that promote melanin production.

♔ After melanin is synthesized, it improves the degradation of tyrosinase, inhibits the transfer of melanosomes to keratinocytes, and has a light stripping effect due to the action of fatty acids. This function is enhanced by the presence of fatty acids and regulates tyrosinase degradation.