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2-Hydroxypropyl-β-cyclodextrin

Short Description:

  • Alias: Hydroxypropyl-beta-cyclodextrin; HP-β-CD; beta-Cyclodextrin 2-hydroxypropyl ethers; HPBCD; HPCD; 2-hydroxypropyl-beta-cyclodextrin; (2-hydroxypropyl)-beta-cyclodextrin; HYDROXYPROPYL-β-CYCLODEXTRIN; beta-Cyclodextrin, 2-hydroxypropyl ether
  • CAS No.: 128446-35-5
  • Molecular Formula: C63H112O42
  • Molecular Weight: 1541.54
  • EINECS No.: 420-920-1

Product Detail

Product Tags

Chemical Structural Formula

product18

Physical Characteristics

Melting Point

278(dec.)

Boiling Point

400

Density

1.05 at 20.3

Refractive Index

125°(C=1, H2O)

Water solubility

Soluble; H2O: 45%(w/v)

Optical Activity

[α]26/D+139°, c=1 in H2O

InChIKey

ODLHGICHYURWBS-FOSILIAISA-N

LogP

-4 at 20

Surface Tension

63.6-65mN/m at 1g/L and 22

20 (2)

Description & Applications

[Overview]

Hydroxypropyl-BETA-cyclodextrin(HP-β-CD) is one of the most intensively researched and widely used cyclodextrin derivatives. It is mainly used in food, medicine and cosmetic industries.

 

[Product Categories]

 

 

 

Injection Grade:

The product has the characteristics of ultra-low beta-cyclodextrin residue, and is suitable for solubilization and aiding of injection drugs.

Oral Grade

The product has the characteristics of solubilization, anti-oxidation, odor removal, sustained release, and targeted drug delivery.

Technical Grade

Mainly used in industrial fields, such as coatings, sterols, pigments, pumping active agents and other industrial purposes.

40% Hydroxypropyl Beta Cyclodextrin Aqueous Solution

Enterprise standard, lower cost

[Applications]

 

 

Pharmaceutical Field

 

Hydroxypropyl-beta-cyclodextrin is an ideal injection solubilizer and pharmaceutical excipient.

(1) Solubilizing and assisting in dissolving, dissolving poorly soluble drugs, improving the solubility of active ingredients in oily drugs;

   Targeted drug delivery and protection of drug ingredient effectiveness.

(2) Improve the bioavailability of the drug, increase the curative effect of the drug or reduce the dosage.

(3) Adjust or control the release rate of the drug to reduce the side effects of the drug.

(4) To cover up bad smell.

Daily Chemical Field

Used as a stabilizer, emulsifier, deodorant, etc. in cosmetic raw materials, it can reduce the stimulation of organic molecules in cosmetics to skin and mucous membrane tissues, enhance the stability of active ingredients, and prevent the volatilization and oxidation of nutrients. It has a certain relative hygroscopicity. Cyclodextrin can also be used as an emulsifier and quality improver in the manufacture of cosmetics. It also has deodorizing (such as halitosis) and antiseptic effects, and can be used in the manufacture of toothpaste and tooth powder.

Industrial Field

Due to the special molecular structure of Hydroxypropyl-beta-cyclodextrin, the application field of this product is continuously expanding. In addition to the use of medicine, it is also used in textiles, air purification, environmental protection, pesticides, flavors & fragrances, toothpaste toothbrushes and other chemical fields.

Packaging

15kg net Carton Box or 20kg net Cardboard Drum.

Storage Conditions

Preserved in well-closed containers in a cool dry place; kept away from direct sunlight, heat and moisture.

Shelf Life

24 months if stored under above conditions.


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