1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
Chemical Structural Formula:
Specifications of our 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(DOPE):
Test Items | Specifications | Test Methods | |
Appearance | White wax solid | Visual | |
Identification | Complies | IR | |
Complies | H-NMR | ||
Molecular Weight | Complies | ESI-MS | |
Assay | 90.0% ~ 110.0% | HPLC | |
Purity | Not less than 90.0% | HPLC | |
Impurities | Lyso-PE | Not more than 1.00% | HPLC |
DOPE-Ac | Not more than 1.00% | ||
OSPE | Not more than 1.00% | ||
DOPE(β) | Not more than 3.00% | ||
Residual Solvents | Dichloromethane | Not more than 600ppm | GC |
n-Hexane | Not more than 290ppm | ||
Ethyl acetate | Not more than 5000ppm | ||
Tetrahydrofuran | Not more than 720ppm | ||
Methanol | Not more than 3000ppm | ||
Moisture | Not more than 2.0% | KF | |
Endotoxin | Not more than 0.1 EU/mg | ChP<1143> | |
Bacteriological Data | TAMC/g | Not more than 100CFU/g | ChP<1105> |
TYMC/g | Not more than 10CFU/g | ||
Elemental Impurities | Not more than 20ppm | ICP-MS |
Application:
Used as one of the LNP Delivery System Excipients for mRNA medicines or drugs.
Packaging:
1g/bottle, 5g/bottle, 10g/bottle or according to the specific requirements from customers.
Recommended Storage Conditions:
Kept at -20 ± 5℃ under an inert atmosphere.
To reduce the moisture absorption, it should be slowly warmed to ambient temperature before opened.
Shelf Life:
24 months if stored under above conditions.