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1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

Short Description:

Product Name: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

Alias: 3-SN-PHOSPHATIDYLETHANOLAMINE, 1,2-DIDEOYL; 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE; 1,2-DI([CIS]-9-OCTADECENOYL)-SN-GLYCERO-3-PHOSPHOETHANOLAMINE; 18:1 PE; L-ALPHA-PHOSPHATIDYLETHANOLAMINE, DIOLEOYL; L-ALPHA-PHOSPHATIDYLETHANOLAMINE, DIOLEOYL (C18:1,[CIS]-9); L-BETA,GAMMA-DIOLEOYL-ALPHA-CEPHALIN; DIOLEOYL PHOSPHATIDYL ETHANOLAMINE; PE(18:1(9Z)/18:1(9Z)); COATSOME ME-8181 (DOPE); L-β,γ-Dioleoyl-α-cephalin; 18:1 (Delta9-Cis) PE (DOPE); Dioleoyl phosphoethanolamine; 1,2-Dioleoyl-sn-glycero-3-PE

Abbreviation: DOPE

CAS No.: 4004-05-1


Product Detail

Product Tags

Chemical Structural Formula:

DOPE结构式-2

Specifications of our 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(DOPE):

Test Items Specifications Test Methods
Appearance White wax solid Visual
Identification Complies IR
Complies H-NMR
Molecular Weight Complies ESI-MS
Assay 90.0% ~ 110.0% HPLC
Purity Not less than 90.0% HPLC
Impurities Lyso-PE Not more than 1.00% HPLC
DOPE-Ac Not more than 1.00%
OSPE Not more than 1.00%
DOPE(β) Not more than 3.00%
Residual Solvents Dichloromethane Not more than 600ppm GC
n-Hexane Not more than 290ppm
Ethyl acetate Not more than 5000ppm
Tetrahydrofuran Not more than 720ppm
Methanol Not more than 3000ppm
Moisture Not more than 2.0% KF
Endotoxin Not more than 0.1 EU/mg ChP<1143>
Bacteriological Data TAMC/g Not more than 100CFU/g ChP<1105>
TYMC/g Not more than 10CFU/g
Elemental Impurities Not more than 20ppm ICP-MS

Application:

Used as one of the LNP Delivery System Excipients for mRNA medicines or drugs.

Packaging:

1g/bottle, 5g/bottle, 10g/bottle or according to the specific requirements from customers.

Recommended Storage Conditions:

Kept at -20 ± 5℃ under an inert atmosphere.

To reduce the moisture absorption, it should be slowly warmed to ambient temperature before opened.

Shelf Life:

24 months if stored under above conditions.


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